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Neuroleptic Malignant Syndrome

Author: Jassin M. Jouria, MD
(Click author's name for bio)

Course Created: 2017

Practice Level: Advanced

This course does not qualify for NBCC credit

No book to buy Duration: 2 hours
4.8 out of 5.0, Based on: 1,984 reviews

Course Summary

Neuroleptic malignant syndrome is a rare, potentially life-threatening complication that usually appears within a clinical setting such as during antipsychotic therapy. Patients who take neuroleptic medications may exhibit symptoms of physical deterioration, confusion and fever. While this condition is not entirely understood, its symptoms are recognizable and typically easily resolved with little or no long-term impact to the patient when caught early.

Course Format

This course contains downloadable online lessons (PDF) and a practice test. When you're ready, purchase the course by clicking the "Add To Cart" button. This will let you take the test, complete the course evaluation and receive your certificate for CE credits.

Learning Objectives

  • Describe Neuroleptic Malignant Syndrome
  • Discuss the clinical presentation and diagnosis of NMS
  • Explain treatments of NMS

Course Syllabus

  • 1.  Introduction

    2.     Overview Of Neuroleptic Malignant Syndrome

    A.   Dopamine Receptors and NMS

    3.    Neuroleptic Drugs

    A.   Neuroleptic Drugs and NMS

    B.   Neuroleptics or Antipsychotics as Sole Cause of NMS

    4.     Clinical Presentation And Diagnosis Of NMS

    A.   Diagnosing NMS

    B.   Distinguishing NMS from Serotonin Syndrome

    C.   NMS and Malignant Hyperthermia

    D.   Other Disorders Mistaken for NMS

    E.   Drugs Causing Symptoms Resembling NMS

    5.      NMS And Serotonergic Receptors

    6.     Part 1 Summary


    Part 2


    1. Introduction

    2.      Overview Of NMS And Treatment Options

    3.    Antipsychotic Use And Discontinuance

    4.     Pharmacologic Therapy For NMS

    1.   Dantrolene

    2.   Bromocriptine

    3.   Lorazepam

    4.   Other Pharmacologic Approaches

    5.   Hypothermia and Regulation Of Body Temperature

    5.      Electroconvulsive Therapy

    6.     Clinical Management Of NMS

    1.   Secondary Complications of NMS Patients

    7.    Prognosis And Recovery From NMS

    8.  Part 2 Summary

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