Course Summary

Practice Level: Advanced

Neuroleptic malignant syndrome is a rare, potentially life-threatening complication that usually appears within a clinical setting such as during antipsychotic therapy. Patients who take neuroleptic medications may exhibit symptoms of physical deterioration, confusion and fever. While this condition is not entirely understood, its symptoms are recognizable and typically easily resolved with little or no long-term impact to the patient when caught early.

Course Format

This course contains downloadable online lessons (PDF) and a practice test. When you’re ready, purchase the course by clicking the “Add To Cart” button. This will let you take the test, complete the course evaluation and receive your certificate for CE credits.

Learning Objectives

  • Describe Neuroleptic Malignant Syndrome
  • Discuss the clinical presentation and diagnosis of NMS
  • Explain treatments of NMS

Course Syllabus

  • Introduction
  • Overview Of Neuroleptic Malignant Syndrome
    • Dopamine Receptors and NMS
  • Neuroleptic Drugs
    • Neuroleptic Drugs and NMS
    • Neuroleptics or Antipsychotics as Sole Cause of NMS
  • Clinical Presentation And Diagnosis Of NMS
    • Diagnosing NMS
    • Distinguishing NMS from Serotonin Syndrome
    • NMS and Malignant Hyperthermia
    • Other Disorders Mistaken for NMS
    • Drugs Causing Symptoms Resembling NMS
  • NMS And Serotonergic Receptors
  • Part 1 Summary
  • Part 2
  • Introduction
  • Overview Of NMS And Treatment Options
  • Antipsychotic Use And Discontinuance
  • Pharmacologic Therapy For NMS
    • Dantrolene
    • Bromocriptine
    • Lorazepam
    • Other Pharmacologic Approaches
    • Hypothermia and Regulation Of Body Temperature
  • Electroconvulsive Therapy
  • Clinical Management Of NMS
    • Secondary Complications of NMS Patients
  • Prognosis And Recovery From NMS
  • Part 2 Summary


Jassin M. Jouria, MD

Jassin M. Jouria is a medical doctor, professor of academic medicine, and medical author. He graduated from Ross University School of Medicine and has completed his clinical clerkship training in various teaching hospitals throughout New York, including King’s County Hospital Center and Brookdale Medical Center, among others. Dr. Jouria  has served as a test prep tutor and instructor for Kaplan. He has developed several medical courses and curricula for a variety of educational institutions. Dr. Jouria has also served on multiple levels in the academic field including faculty member and Department Chair. Dr. Jouria continues to serves as a Subject Matter Expert for several continuing education organizations covering multiple basic medical sciences.

Accreditation Approval Statements

This course does not qualify for NBCC credit. is approved by the American Psychological Association to sponsor continuing education for psychologists. maintains responsibility for this program and its content.

Courses have been approved by, as a NAADAC Approved Education Provider, for educational credits. NAADAC Provider #91345 is responsible for all aspects of the programming.

We are committed to providing our learners with unbiased information. CE4Less never accepts commercial support and our authors have no significant financial or other conflicts of interest pertaining to the material.

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